Aseptic meningitis complicating immunoglobulin therapy in AIDP

Introduction:
A case of aseptic meningitis due to intravenous immunoglobulin is being reported.

Aim:
To learn rare side effect of intravenous immunoglobulin.

Case study:
Intravenous immunoglobulin is a safe therapy in many diseases. Side effects due to IVIG therapy usually are mild. Rarely can it lead to meningitis. We encountered aseptic meningitis in patientwith acute inflammatory demyelinating polyneuropathy following IVIG.

Results and discussion:
The incidence of drug-induced aseptic meningitis (DIAM) is unknown. Other drugs that have been associated with DIAM include NSAIDs, ranitidine, carbamazepine, vaccines against hepatitis B and mumps, immunoglobulin, and radiographic agents. Most of the reported cases had ITP as the primary disease or received high dose IVIG therapy. It has rarely been reported in patient with AIDP.

Conclusions:
Recognition of aseptic meningitis as an adverse reaction following IVIG therapy is important as it may be treated effectively.

CONFLICT OF INTEREST

None declared.

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