CASE REPORT
Inflammatory tumour in the course of microscopic polyangiitis may mimic testicular cancer
Arkadiusz Bociek 1  
,   Ada Bielejewska 1  
,   Martyna Bociek 2  
,   Andrzej Jaroszyński 1  
 
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1
Faculty of Medicine and Health Science, Jan Kochanowski University in Kielce, Poland
2
Faculty of Medical Science, Higher School of Economy, Law and Medical Science of Professor Edward Lipiński in Kielce, Poland
CORRESPONDING AUTHOR
Ada Bielejewska   

IX Wieków Kielc 19a, 25-317 Kielce, Poland. Tel.: +48 607 837 922.
Submission date: 2019-05-11
Acceptance date: 2019-06-12
Online publication date: 2019-12-16
 
Pol. Ann. Med. 2020;27(1):59–61
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Microscopic polyangiitis (MPA) is an antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) that can affect any organ. Sometimes, untypical localization, together with an unusual clinical manifestation of tumour-resembling inflammatory changes, can cause a delay in diagnosis and proper treatment.

Aim:
The aim of this study was to expose the case of very rare location of MPA manifestation.

Case study:
In this paper, we present the case of inflammatory testicular tumour-like lesion that was a manifestation of MPA and mimicked testicular cancer.

Results and discussion:
It is probably first desribed case of MPA mimicking testicular cancer. However, in the literature some others AAV manifestation in that location can be found. In these patients orchiectomy was recommended much more often than a testicular biopsy.

Conclusions:
We conclude that in case of a patient with untypical features of a tumour, inflammatory processes, including vasculitis, should be taken into consideration in differential diagnosis.

CONFLICT OF INTEREST
None declared.
FUNDING
None declared.
 
REFERENCES (8)
1.
Al-Hussain T, Hussein MH, Conca W, Al Mana H, Akhtar M. Pathophysiology of ANCA-associated Vasculitis. Adv Anat Pathol. 2017;24(4):226–234. https://doi.org/10.1097/PAP.00....
 
2.
Miyawaki Y, Katsuyama T, Sada KE, Taniguchi K, Kakio Y, Wada J. Development of intracerebral hemorrhage in the short-term clinical course of a patient with microscopic polyangiitis without neurological symptoms at diagnosis: an autopsy case. CEN Case Reports. 2016;5(2):173–178. https://dx.doi.org/10.1007%2Fs....
 
3.
Kao C, Zhang C, Ulbright TM. Testicular Hemorrhage, Necrosis, and Vasculopathy. Am J Surg Pathol. 2014;38(1):34–44. https://doi.org/10.1097/PAS.0b....
 
4.
Lee SS, Tang SH, Sun GH, Yu CP, Jin JS, Chang SY. Limited Wegener’s granulomatosis of the epididymis and testis. Asian J Androl. 2006;8(6):737–739. https://doi.org/10.1111/j.1745....
 
5.
Dalpiaz A, Schwamb R, Miao Y, Gonka J, Walzter W, Khan SA. Urological manifestations of henoch-schonlein purpura: A review. Curr Urol. 2014;8(2):66-73. https://doi.org/10.1159/000365....
 
6.
Kariv R, Sidi Y, Gur H. Systemic vasculitis presenting as a tumorlike lesion. Four case reports and an analysis of 79 reported cases. Medicine (Baltimore); 2000;79(6):349–359. https://doi.org/10.1097/000057....
 
7.
Brimo F, Lachapelle J, Epstein JI. Testicular vasculitis: A series of 19 cases. Int Braz J Urol. 2011;37(2):279. http://dx.doi.org/10.1590/S167....
 
8.
8 Hernández-Rodríguez J, Tan CD, Koening CL, Khasnis A, Rodríguez ER, Hoffman GS. Testicular vasculitis: Findings differentiating isolated disease from systemic disease in 72 patients. Medicine (Baltimore). 2012;91(2):75–85. https://doi.org/10.1097/MD.0b0....