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CASE REPORT
Kimura disease – A case report and review of the literature
| 1 | Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia |
| 2 | Darul Ehsan Medical Centre, Selangor, Malaysia |
| 3 | Malaysian Research Institute of Aging, Universiti Putra Malaysia, Malaysia |
| 4 | Department of ENT, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia |
| 5 | Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia |
CORRESPONDING AUTHOR
Wan Aliaa Wan Sulaiman
Neurology Unit, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. Tel.: +60 3 8947 2300; fax: +60 3 8947 2585.
Neurology Unit, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. Tel.: +60 3 8947 2300; fax: +60 3 8947 2585.
Submission date: 2016-05-01
Acceptance date: 2016-11-10
Online publication date: 2017-02-15
Publication date: 2019-12-15
Pol. Ann. Med. 2017;24(1):64–66
KEYWORDS
ABSTRACT
Introduction:
Kimura disease (KD) is a benign chronic inflammatory disorder attributed to an immunemediated hypersensitivity. KDis commonly presented with unilateral subcutaneous tissue swelling in the head and neck area. The course is usually benign except for the potential cosmetic disfigurement. There is no consensus for the treatment of recurrent disease.
Aim:
To illustrate a case of an uncommon cause of head and neck swelling.
Case study:
A 41-year-old male presented with a recurrent painless swelling at his of right lower cheek swelling for 6-months. Head and neck examination revealed a 7 × 7 cm firm, non tender mass over the right mandibular region. Other systemic examination was unremarkable. Magnetic resonance imaging of the mass showed a well defined lesion 6 × 3 × 5 cm in size anterior to the right body of mandible. Surgical excision of the mass was done and histopathological examination of the specimen showed fibrocollagenous and fibrofatty tissue infiltrated by chronic inflammatory cells in the pattern of perivascular lymphoid aggregates. The infiltrate is composed predominantly of small lymphocytes and eosinophils.
Results and discussion:
Here we described a rare cause of painless subcutaneous head and neck swelling that occurred in a middle-aged Asian man. KD usually presents as a painless subcutaneous soft-tissue swellings and associated with regional lymphadenopathy in the head and neck region. Diagnosis of KD is always a clinical dilemma with no specific diagnostic guideline. Though there is no consensus for the treatment of recurrent disease, the overall outcome is good as there is no association with malignancy.
Conclusions:
KD should be considered in the differential diagnosis of a recurrent head and neck mass.
Kimura disease (KD) is a benign chronic inflammatory disorder attributed to an immunemediated hypersensitivity. KDis commonly presented with unilateral subcutaneous tissue swelling in the head and neck area. The course is usually benign except for the potential cosmetic disfigurement. There is no consensus for the treatment of recurrent disease.
Aim:
To illustrate a case of an uncommon cause of head and neck swelling.
Case study:
A 41-year-old male presented with a recurrent painless swelling at his of right lower cheek swelling for 6-months. Head and neck examination revealed a 7 × 7 cm firm, non tender mass over the right mandibular region. Other systemic examination was unremarkable. Magnetic resonance imaging of the mass showed a well defined lesion 6 × 3 × 5 cm in size anterior to the right body of mandible. Surgical excision of the mass was done and histopathological examination of the specimen showed fibrocollagenous and fibrofatty tissue infiltrated by chronic inflammatory cells in the pattern of perivascular lymphoid aggregates. The infiltrate is composed predominantly of small lymphocytes and eosinophils.
Results and discussion:
Here we described a rare cause of painless subcutaneous head and neck swelling that occurred in a middle-aged Asian man. KD usually presents as a painless subcutaneous soft-tissue swellings and associated with regional lymphadenopathy in the head and neck region. Diagnosis of KD is always a clinical dilemma with no specific diagnostic guideline. Though there is no consensus for the treatment of recurrent disease, the overall outcome is good as there is no association with malignancy.
Conclusions:
KD should be considered in the differential diagnosis of a recurrent head and neck mass.
CONFLICT OF INTEREST
None declared.
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