RESEARCH PAPER
The evaluation of selected shellfish as a source of niacin in nutrition and therapy of modern human
 
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1
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Poland
2
Department of Food Sciences, Medical University of Gdańsk, Poland
CORRESPONDING AUTHOR
Michał Majewski   

Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Żołnierska 14 C, 10-561 Olsztyn, Poland. Tel.: +48 89 524 61 88; fax: +48 89 524 61 88.
Submission date: 2013-12-02
Acceptance date: 2014-01-20
Online publication date: 2014-04-22
Publication date: 2020-03-26
 
Pol. Ann. Med. 2014;21(1):14–19
 
KEYWORDS
ABSTRACT
Introduction:
The presence of fish and seafood in the diet of people at high risk of heart disease, pregnant women and the elderly is conducive to the preservation of health. Food originating from the sea is a good source of niacin and should be consumed by all, regardless of age and/or physiological state. Therefore, it is recommended by physicians and nutritionists.

Aim:
The aim of this study was to determine the content of niacin in selected seafood and to evaluate these products as a potential source of niacin.

Material and methods:
The content of niacin was determined by the microbial method. The vitamin was extracted from the analyzed samples using enzymatic hydrolysis.

Results:
A portion of 100 g seafood implements the standard daily requirement in range of 4.43%–8.21% for women and 3.88%–7.19% for men, respectively.

Discussion:
Fish and seafood consumption has a tendency to increase all over the world, whereas in some countries (Poland) it persists insufficient with a declining tendency. Considering high nutritive value, the analyzed shellfish are recommended as valuable ingredient of diet. Increased consumption of seafood might contribute to reduce the risk of civilization diseases morbidity.

Conclusions:
The niacin analysis that was conducted showed differences between the various types of seafood. Among the analyzed seafood, the best source of niacin came from the meat of clams.

CONFLICT OF INTEREST
None declared.
 
REFERENCES (37)
1.
Lebiedzińska A, Majewski M, Szefer P. Butterfish as a source of niacin. Rocz Państw Zakx Hig. 2008;59(2):197–201 [in Polish].
 
2.
Lebiedzińska A, Majewski M, Szefer P. Niacin content in canned tuna fish. Bromat Chem Toksykol. 2008;1:29–33 [in Polish].
 
3.
Watanabe F. Vitamin B12 sources and bioavailability. Exp Biol Med (Maywood). 2007;232(10):1266–1274.
 
4.
Zdrojewska I, Lebiedzińska A, Szefer P. Selected seafood as the components of a highly nutritional diet. Rocz Państw Zakx Hig. 2005;56(2):131–137 [in Polish].
 
5.
Oehlenschläger J. Seafood: nutritional benefits and risk aspects. Int J Vitam Nutr Res. 2012;82(3):168–176.
 
6.
Gebauer SK, Psota TL, Harris WS, et al. n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits. Am J Clin Nutr. 2006;83(6 suppl):1526S–1535S.
 
7.
Graham I, Atar D, Borch-Johnsen K, et al. European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J. 2007;28(19):2375–2414.
 
8.
King I, Childs MT, Dorsett C, et al. Shellfish: proximate composition, minerals, fatty acids, and sterols. J Am Diet Assoc. 1990;90(5):677–685.
 
9.
Villegas R, Xiang YB, Elasy T, et al. Fish, shellfish, and longchain n-3 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women. Am J Clin Nutr. 2011;94(2):543–551.
 
10.
Kim J, Jo I. Grains, vegetables, and fish dietary pattern is inversely associated with the risk of metabolic syndrome in South Korean adults. J Am Diet Assoc. 2011;111(8):1141–1149.
 
11.
Baik I, Abbott RD, Curb JD, et al. Intake of fish and n-3 fatty acids and future risk of metabolic syndrome. J Am Diet Assoc. 2010;110(7):1018–1026.
 
12.
Fabbrini E, Mohammed BS, Korenblat KM, et al. Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. J Clin Endocrinol Metab. 2010;95(6):2727–2735. http://dx.doi.org/10.1210/jc.2....
 
13.
Jackevicius CA, Tu JV, Ko DT, et al. Use of niacin in the United States and Canada. JAMA Intern Med. 2013;173(14):1379–1381.
 
14.
McKenney JM. Combination treatment with atorvastatin plus niacin provides effective control of complex dyslipidemias: a literature review. Postgrad Med. 2012;124(1):7–20.
 
15.
Robinson JG. What is the role of advanced lipoprotein analysis in practice? J Am Coll Cardiol. 2012;60(25):2607–2615.
 
16.
Kamanna VS, Kashyap ML. Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents? Am J Cardiol. 2007;100(11A):S53–S61.
 
17.
Vega GL, Cater NB, Meguro S, et al. Influence of extendedrelease nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia. Am J Cardiol. 2005;95(11):1309–1313.
 
18.
Matheson EM, Mainous 3rd AG, Hill EG, et al. Shellfish consumption and risk of coronary heart disease. J Am Diet Assoc. 2009;109(8):1422–1426.
 
19.
Oliver MF. Control of free fatty acids during acute myocardial ischaemia. Heart. 2010;96(23):1883–1884.
 
20.
Kang I, Kim SW, Youn JH. Effects of nicotinic acid on gene expression: potential mechanisms and implications for wanted and unwanted effects of the lipid-lowering drug. J Clin Endocrinol Metab. 2011;96(10):3048–3055.
 
21.
Lavigne PM, Karas RH. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression. J Am Coll Cardiol. 2013;61(4):440–446.
 
22.
Brouwers MC, Stehouwer CD. Niacin in cardiovascular patients receiving statins. N Engl J Med. 2012;366(13):1255. http://dx.doi.org/10.1056/NEJM....
 
23.
Davidson M. A review of the current status of the management of mixed dyslipidemia associated with diabetes mellitus and metabolic syndrome. Am J Cardiol. 2008;102(12A):19L–27L. http://dx.doi.org/10.1016/j.am....
 
24.
Phan BA, Muñoz L, Shadzi P, et al. Effects of niacin on glucose levels, coronary stenosis progression, and clinical events in subjects with normal baseline glucose levels (<100 mg/dl): a combined analysis of the Familial Atherosclerosis Treatment Study (FATS), HDLAtherosclerosis Treatment Study (HATS), Armed Forces Regression Study (AFREGS), and Carotid Plaque Composition by MRI during lipid-lowering (CPC) study. Am J Cardiol. 2013;111(3):352–355.
 
25.
Hamoud S, Kaplan M, Meilin E, et al. Niacin administration significantly reduces oxidative stress in patients with hypercholesterolemia and low levels of high-density lipoprotein cholesterol. Am J Med Sci. 2013;345(3):195–199.
 
26.
Vítek L, Vaníková J, Nachtigal P. Niacin inhibits vascular inflammation via the induction of heme oxygenase-1. Circulation. 2012;126(7):99.
 
27.
Nelson RH, Vlazny D, Smailovic A, et al. Intravenous niacin acutely improves the efficiency of dietary fat storage in lean and obese humans. Diabetes. 2012;61(12):3172–3175.
 
28.
Jacobson TA. A ‘‘hot’’ topic in dyslipidemia management – ‘‘how to beat a flush’’: optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention. Mayo Clin Proc. 2010;85(4):365–379.
 
29.
AOAC. Niacin and Niacinamide (Nicotinic Acid and Nicotinamide) in Vitamin Preparations. 2003. Maryland. http://www.eoma.aoac.org/metho... [accessed 10.10.2013].
 
30.
Ndaw S, Bergaentzle M, Hasselmann C. Enzymatic extraction procedure for liquid chromatographic determination of niacin in foodstuffs. Food Chem. 2002; 78(1):129–134.
 
31.
Eitenmiller RR, Landen WO. Vitamin Analysis for the Health and Food Sciences. Boca Raton, FL: CRC Press; 1999.
 
32.
Jarosz M, Bułhak-Jachymczyk B. Standards of Human Nutrition. Basic Prevention of Obesity and Non-communicable Diseases. Warszawa: PZWL; 2008 [in Polish].
 
33.
Pieniak Z, Verbeke W, Scholderer J. Health-related beliefs and consumer knowledge as determinants of fish consumption. J Hum Nutr Diet. 2010;23(5):480–488.
 
34.
Chowdhury R, Stevens S, Gorman D, et al. Association between fish consumption, long chain omega 3 fatty acids, and risk of cerebrovascular disease: systematic review and meta-analysis. BMJ. 2012;345:e6698. http://dx.doi.org/10.1136/bmj.....
 
35.
He K, Merchant A, Rimm EB, et al. Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men. Stroke. 2004;35:169–174. http://dx.doi.org/10.1161/01.S....
 
36.
Lebiedzinska A. Fish and shellfish as a source of vitamins B – own results in a view of literature data. Polish J Environ Stud. 2006;15(2):1322–1327.
 
37.
Woo CK, Bahna SL. Not all shellfish ‘‘allergy’’ is allergy!. Clin Transl Allergy. 2011;1:3. http://dx.doi.org/10.1186/2045... 7022-1-3.